Blood pressure still not where you want it to be? You're not alone.
In a government survey approximately 45% of US adults with high blood pressure (BP) had uncontrolled BP numbers*. If your blood pressure is still not where you want it to be, in addition to lifestyle and diet changes, you may benefit from prescription TEKTURNA. Taken once a day, TEKTURNA may help you get closer to your blood pressure goal.
TEKTURNA targets renin to help lower high blood pressure
TEKTURNA is a scientifically innovative treatment that targets an enzyme in certain tissues in the body and in the bloodstream called renin. Renin can start a process that narrows blood vessels. By inhibiting renin, TEKTURNA helps:
TEKTURNA is a scientifically innovative treatment that targets an enzyme in the bloodstream called renin, which can start a process that narrows blood vessels, leading to high blood pressure.
TEKTURNA HCT lowers blood pressure with two different components
TEKTURNA HCT offers two FDA-approved prescription medicines—aliskiren (TEKTURNA), a direct renin inhibitor (DRI), and hydrochlorothiazide, a diuretic (water pill)—in one tablet.
1. Here’s how the TEKTURNA component works:
Renin is an enzyme that can start a process that narrows blood vessels, leading to high blood pressure. TEKTURNA inhibits renin, which helps:
2. Here’s how the hydrochlorothiazide (HCTZ) component works:
In a medical study, TEKTURNA was combined with HCTZ, a diuretic, also called a water pill. People who took the combination of TEKTURNA and HCTZ, achieved greater reduction in their blood pressure than those taking TEKTURNA or HCTZ alone. TEKTURNA HCT combines these two components in a single once-daily tablet.
TEKTURNA and TEKTURNA HCT are prescription medicines for adults used to treat high blood pressure.
TEKTURNA HCT may be used when one medicine to lower your high blood pressure is not enough, or as the first medicine to lower high blood pressure if your doctor decides you are likely to need more than one medicine to reach your blood pressure goal.
IMPORTANT WARNING: TEKTURNA or TEKTURNA HCT can cause harm or death to an unborn baby. Talk to your doctor about other ways to lower your blood pressure if you plan to become pregnant. If you get pregnant, stop taking TEKTURNA or TEKTURNA HCT and tell your doctor right away.
Do not take TEKTURNA or TEKTURNA HCT if you have diabetes and are taking a kind of medicine called an angiotensin receptor blocker (ARB) or angiotension-converting enzyme inhibitor (ACEI); or if you are allergic to aliskiren or any of their other ingredients.
In addition, do not take TEKTURN HCT if you make very little or no urine due to kidney problems, or if you have allergic reactions to certain medicines called sulfonamides or hydrocholorthiazide.
Aliskiren, a medicine in TEKTURNA and TEKTURNA HCT, can cause difficulty breathing or swallowing, tightness of the chest, hives, general rash, swelling, itching, dizziness, vomiting, or abdominal pain (signs of a severe allergic reaction called angioedema). TEKTURNA and TEKTURNAL HCT can also cause swelling of the face, lips, tongue, throat, arms and legs, or the whole body (signs of angioedema). Stop taking TEKTURNA or TEKTURNA HCT and get medical help right away and tell your doctor if you get any one or more of these symptoms. Angioedema can happen at any time while you are taking TEKTURNA or TEKTURNA HCT.
Your blood pressure may get too low if you also:
Lie down if you feel faint or dizzy. Call your doctor right away.
Tell your doctor about all of your medical conditions, including: if you have kidney problems; if you have ever had an allergic reaction, called angioedema, to another blood pressure medicine; or if you are breastfeeding. It is not known if TEKTURNA or TEKTURNA HCT passes into your breast milk and can harm your baby. You should not take TEKTURNA or TEKTURNA HCT and breastfeed.
Tell your doctor right away if you have eye pain or a decrease in vision.
Also, tell your doctor about all the medicines you take, including a kind of medicine to control blood pressure, called an angiotensin receptor blocker or ACE inhibitor, cholesterol lowering medicines (like simvastatin, atorvastatin, cholestyramine, colestipol), water pills (especially potassium-sparing diuretics), medicines to treat fungal infections (like itraconazole or ketoconazole), cyclosporine, potassium-containing medicines, potassium supplements, salt substitutes containing potassium, or NSAIDs (like ibuprofen or naproxen), including Cyclooxygenase-2 (COX-2) inhibitors.
Additionally, if you take TEKTURNA HCT, tell your doctor if you have liver problems, have allergies or asthma, have lupus, or if you take lithium or medicine to treat diabetes.
The most common side effects of TEKTURNA and TEKTURNA HCT include:
Less common side effects include rash and severe skin reactions.
You are encouraged to report side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Please see full Prescribing Information and Patient Information, including IMPORTANT WARNING, for TEKTURNA.
Please see full Prescribing Information and Patient Information, including IMPORTANT WARNING, for TEKTURNA HCT.